Hemosiderosis (plural: haemosideroses) is a general term referring to the accumulation of hemosiderin, which particularly occurs in the reticuloendothelial system (RES) and does not cause organ damage.
Some causes include:
- frequent transfusion
- high erythrogenic requirements (hemolytic anemia, myelodysplasia)
- mainly depositional siderosis in RES from transfusion
- increased duodenal iron absorption may lead to hemochromatosis (non-RES iron deposition)
- bantu siderosis: rare cause in Africa due to iron-laden locally brewed beer