Neurofibrillary tangles

Neurofibrillary tangles (NFTs) are abnormal cytoplasmic accumulations of tau proteins, found in neuronal and glial cells of the central nervous system. They are responsible for a number of neurodegenerative diseases (collectively known as tauopathies) including 1:

Neurofibrillary tangles are also a prominent feature of Alzheimer disease, which in addition demonstrates extracellular neuritic plaques.

Article information

rID: 13022
Section: Pathology
Synonyms or Alternate Spellings:
  • Neurofibrillary tangles (NFTs)

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Cases and figures

  • Image courtesy of...
    Diagram : neurofibrillary tangle formation
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