Primary pleural lymphoma

Dr Owen Kang and Dr Henry Knipe et al.

Primary pleural lymphoma is extremely rare, especially in immunocompetent patients.

Primary pleural lymphoma accounts for <0.5% of all non-Hodgkin lymphoma 2 and ~2.5% of primary chest wall tumors 4

Primary pleural lymphoma may be Hodgkin or non-Hodgkin lymphoma with diffuse large B-cell accounting for the majority (60%) of cases 4

Primary pleural lymphoma has been described in the setting of chronic inflammation or in immunocompromised patients 1:

  • body-cavity (i.e. pleural, pericardial or peritoneal) based in patients with HIV
  • associated with tuberculosis pyothorax

Case reports exist of primary pleural lymphoma in immunocompetent patients with other proposed causative factors 4:

Primary pleural lymphoma may presents with non-specific features 3,4:

Other types of pleural tumors should be considered. 


Article information

rID: 33127
Synonyms or Alternate Spellings:
  • Primary lymphoma of pleura

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Cases and figures

  • Case 1
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  • Case 2
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