Anaplastic astrocytoma

Case contributed by Dr Bruno Di Muzio


Patient referred for evaluation after seizure.

Patient Data

Age: 46
Gender: Female

There is a lesion centered in the right temporal lobe which demonstrates extension into the posterior aspect of the frontal lobe in the precentral gyrus and the anterior aspect of the parietal lobe in the postcentral gyrus.

There is a small cystic appearing area within the anterior aspect of the lesion felt to represent a focus of necrosis.

There is a small amount of enhancement within the mid-portion portion and posterior aspects of the lesion. No evidence of hemorrhage or calcification appreciated. Moderate amount of surrounding vasogenic edema appreciated. Very minor mass effect on the adjacent lateral ventricle.

No midline shift. Ventricular size within normal limits and the basal cisterns are patent.

There are a few small foci of high signal within the white matter of the left hemisphere which are felt to be nonspecific. Incidental note of sinus disease. Vascular flow voids preserved.


Right temporal lobe tumor with involvement of the pre and postcentral gyri. Given the enhancement of the lesion, this is felt to most likely represent a grade 3 anaplastic astrocytoma.

Case Discussion

This case corresponds to a pathologically proven anaplastic astrocytoma, which is a WHO grade III tumor. 

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Case information

rID: 39124
Published: 21st Aug 2015
Last edited: 14th Aug 2019
Tag: rmh
Inclusion in quiz mode: Included

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