Splenic thorotrastosis

Case contributed by Dr Rohit Sharma

Presentation

Previous Thorotrast contrast administration.

X-ray

Plain abdominal radiograph

Abdominal radiograph shows multiple micronodular hyperdense lesions speckled in the left hypochondrium.

CT

Select illustrative CT non-contrast axial slice

Select illustrative axial slice demonstrates multiple micronodular hyperdense lesions in the spleen.

Case Discussion

In this patient with previous known administration of Thorotrast contrast, findings are in-keeping with splenic accumulation (or thorotrastosis).

Thorotrast is a suspension of radioactive thorium dioxide that was used as a contrast agent until the 1950s. Following administration, it typically accumulates within the body - particularly the liver, spleen, and peripancreatic lymph nodes. Radiographically, it is seen as metallic densities which may have a multinodular, miliary or diffuse pattern of distribution. Due to Thorotrast being an alpha emitter with a very long half-life, it is highly carcinogenic, and thus is no longer in use.

 

Case uploaded on behalf of and courtesy of Dr Paul McCoubrie.

PlayAdd to Share

Case information

rID: 73597
Published: 16th Jan 2020
Last edited: 16th Jan 2020
Inclusion in quiz mode: Excluded

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.