Articles

Articles are a collaborative effort to provide a single canonical page on all topics relevant to the practice of radiology. As such, articles are written and edited by countless contributing members over a period of time. A global group of dedicated editors oversee accuracy, consulting with expert advisers, and constantly reviewing additions.

25 results found
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Breast MRI

Breast MRI is the most sensitive method for detection of breast cancer. Depending on international health regulations, it is either applied for screening of women at high risk for developing breast cancer (e.g. BRCA1 and BRCA2 carriers), as an additional diagnostic test in pretherapeutic breast ...
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British Thoracic Society guidelines for pulmonary nodules

British Thoracic Society guidelines for pulmonary nodules were published in August 2015 for the management of pulmonary nodules seen on CT. In the United Kingdom, they supersede the Fleischner Society guidelines. They are based initially on identifying whether the nodule is solid or subsolid an...
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Causes of perfusion defects on a VQ scan

There are several causes leading to a perfusion defect on a VQ scan with an acute pulmonary embolus being only one of them: Vascular causes acute pulmonary embolus previous pulmonary embolus (including fat embolism, thromboembolism, air embolism, tumor) vasculitides affecting the pulmonary v...
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Computed tomography texture analysis

Computed tomography texture analysis (or CTTA) is a method to obtain new useful biomarkers that provide objective and quantitative assessment of tumor heterogeneity by analyzing the differences and patterns within the pixel values of an image. CTs can be worked with as a matrix of numbers, corre...
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Congenital heart disease chest x-ray (an approach)

With the advent of echocardiography, and cardiac CT and MRI, the role of chest x-rays in evaluating congenital heart disease has been largely been relegated to one of historical and academic interest, although they continue to crop up in radiology exams. In most instances a definite diagnosis ca...
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Fluid-fluid levels in bone tumors

Fluid-fluid levels in bone tumors is a commonly encountered finding, both in benign as well as malignant bone tumors, and can be used to differentiate between the two. Method of assessment On the sagittal T2W image: measure the length of the largest fluid-fluid level (A) measure the maximum ...
Article

Giant breast masses

Many patients, particularly in developing countries, can present late with giant breast masses. They may be single or multiple and either benign or malignant. Many of these conditions are indistinguishable on physical examination alone. Some of these lesions require mastectomy while others can b...
Article

Hemorrhage exclusion sign (prostate)

The hemorrhage exclusion sign can be a useful MRI finding following prostate biopsy. Pathology The normal prostate produces high concentrations of citrate, which among other properties, acts as an anticoagulant 1. As tumor cells are dysfunctional, they will produce lower levels of citrate than...
Article

Head and neck cancer therapy response interpretation (Hopkins criteria)

The head and neck cancer therapy response interpretation (Hopkins criteria) is a qualitative system of interpretation for therapy response assessment using PET-CT. Background Widely used options for therapy response assessment are clinical examination, histopathology, CT and MR imaging, howeve...
Article

Hyperechoic liver lesions

A hyperechoic liver lesion on ultrasound can arise from a number of entities, both benign and malignant. A benign hepatic hemangioma is the most common entity encountered, but in patients with atypical findings or risk for malignancy, other entities must be considered. Benign hepatic hemangiom...
Article

Intraventricular masses (an approach)

The ventricular system of the brain plays host to a variety of unique tumors, as well as tumors that are more frequently seen elsewhere (e.g. meningiomas). Besides, some intra-axial (parenchymal) masses can be mostly exophytic and thus appear mostly intraventricular. A systematic approach taking...
Article

Lipoma vs well-differentiated liposarcoma

There a number of features that can help distinguish between lipoma and well-differentiated liposarcoma. This article relates to superficial well-differentiated liposarcomas that typically occur in the extremities, also known as atypical lipomatous tumors, and not retroperitoneal liposarcoma. E...
Article

Lobectomy (lung)

A lobectomy (plural: lobectomies) is the complete resection of one lobe of the lung and is the commonest lung surgery performed for bronchogenic carcinoma. Technique A posterolateral thoracotomy is the commonest approach for the resection of lung malignancies. For other surgical approaches for...
Article

MRI targeted prostate biopsy

MRI targeted prostate biopsy refers to an imaging targeted technique rather than the traditional systematic approach of a prostate biopsy after respective imaging with multiparametric MRI (mpMRI) of the prostate. As a consequence of the recent advances of multiparametric MRI (mpMRI) of the pros...
Article

Pyrexia of unknown origin

A pyrexia of unknown origin, commonly shortened to PUO and also known as a fever of unknown origin (FUO), was originally defined in 1961 as the condition in which the core body temperature is >38.3oC for a period of three weeks or more, with no diagnosis reached after one week of inpatient inves...
Article

RANO criteria for glioblastoma

Response assessment in neuro-oncology criteria (RANO), published in 2010 1, are used to assess response to first-line treatment of glioblastoma (as well as lower grade astrocytoma 3) and have largely superseded the older Macdonald criteria (which only dealt with glioblastoma multiforme) 2. For ...
Article

Reporting and Data Systems (disambiguation)

In recent years there has been a proliferation of Reporting and Data Systems (RADS), which have been proposed - and in many cases widely adopted - as standardized systems for the reporting of imaging of various body organs, often, but certainly not always, with a focus on oncological disease 2. ...
Article

Screening for breast cancer

Screening for breast cancer includes activities which test members of asymptomatic populations for breast cancer. Many advanced countries have breast screening programs. The most widely adopted method for breast cancer screening is mammography. There are few areas in imaging fraught with more c...
Article

Selective internal radiation therapy

Selective internal radiation therapy (SIRT), also know as hepatic radioembolization, is a relatively new and developing modality for treating non-resectable liver tumors. The procedure consists of a transcatheter injection of radioactive particles via the hepatic artery.  It is generally consid...
Article

Solitary pulmonary nodule (an approach)

A solitary pulmonary nodule, according to the Nomenclature Committee of the Fleischner Society, is defined as a rounded opacity, well or poorly-defined on a conventional radiograph, measuring up to 3 cm in diameter and is not associated with lymphadenopathy, atelectasis, or pneumonia. Several r...
Article

Sonographic features of malignant lymph nodes

Lymphadenopathy is quite common, and it can be very difficult to differentiate malignant lymphadenopathy from reactive nodal enlargement. Several gray scale and color Doppler features favor malignancy in a lymph node. Gray scale parameters that favor malignancy size: larger-more likely malign...
Article

Split bolus technique

The split bolus technique is a CT imaging investigation used in patients with hematuria aiming to put together, in a single image acquisition, both the nephrographic and renal excretory phases and thus reducing the radiation dose of the study. It is a CT protocol adopted for some institutions fo...
Article

Tumor pseudoresponse

Tumor pseudoresponse, also known just as pseudoresponse, refers to the phenomenon of tumors appearing to respond to a specific treatment on imaging criteria, when the lesion actually remains stable or has even progressed. The term is largely used in brain tumors imaging follow-up, especially fo...
Article

Volume doubling time

The volume doubling time (VDT) is an important volumetric parameter primarily used in lung cancer screening and follow-up by chest CT. Volume doubling time is defined as the time required for a growing nodule to double its volume. A longer VDT suggests a more benign course, whilst a short VDT is...
Article

Weight loss

A clinical presentation of weight loss is extremely common and often a source of marked anxiety for the patient. The commonest cause of unintentional weight loss (UWI) is gastrointestinal tract disease, and not malignancy. Terminology The published literature lacks a consistent definition of w...

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